BDBM147482 US8962608, 2-5

SMILES NC(=O)c1cn(nc1Nc1ccccc1)C1[C@H](O)CCC[C@H]1C#N

InChI Key InChIKey=GVFQMFLSGMSFPE-NFCBODTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147482   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM147482(US8962608, 2-5)
Affinity DataIC50:  700nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent